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42.
Vivek Kant 《Theoretical Issues in Ergonomics Science》2018,19(5):606-635
Human Factors and Ergonomics (HFE) recognises itself as a design-driven, systemic and scientific discipline geared towards well-being and performance. Being a scientific discipline and design-oriented requires that the epistemic basis of science and design/engineering be fully comprehended. In interdisciplinary research where these two viewpoints meet, there are often dilemmas posed in terms of knowledge construction and labelling of activity. Therefore, this article scrutinises these two orientations and addresses the differences and commonalities, using case studies from engineering and psychological science (both constituents of HFE). Based on these insights, a way forward is suggested in terms of (1) a reflexive engagement with epistemic concepts and methods; (2) finding a conceptual space for balancing and bridging the science-engineering divide; (3) comprehending ‘design-thinking/design knowledge’ and not treating it as an application of science; (4) providing emphasis on problem formulation and practices of HFE focusing on developing them in systemic terms. 相似文献
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Comprehensive design schemes and specifications have progressively shaped Master-Planned Communities (MPCs). The market largely predetermines these outcomes, with background input from communities. Therefore, this paper endeavours to define the fundamental structures that generate differences between market actors and residents within the North Lakes MPC. This study employs ‘habitus theory’, which is a sociological phenomenon describing the divergence of personal outlooks and expertise. The application of this theory is thus illustrative of the evolution of distinct observations within MPCs. Contemporary studies have under-researched these inherent gaps between communities, authorities, and critics, and these frictions could be exacerbated within restrictive developmental contexts. Epistemic and objectified content analyses collated over many years and sources will uncover the underlying differences between the relevant groups. These analyses will enable the progression of a framework for understanding power relation biases and how reflexivity can enhance current consultative methods. 相似文献
45.
Sen Yan 《国际生产研究杂志》2020,58(6):1724-1740
Facility disruptions in the supply chain often lead to catastrophic consequences, although they occur rarely. The low frequency and non-repeatability of disruptive events also make it impossible to estimate the disruption probability accurately. Therefore, we construct an uncertain programming model to design the three-echelon supply chain network with the disruption risk, in which disruptions are considered as uncertain events. Under the constraint of satisfying customer demands, the model optimises the selection of retailers with uncertain disruptions and the assignment of customers and retailers, in order to minimise the expected total cost of network design. In addition, we simplify the proposed model by analysing its properties and further linearise the simplified model. A Lagrangian relaxation algorithm for the linearised model and a genetic algorithm for the simplified model are developed to solve medium-scale problems and large-scale problems, respectively. Finally, we illustrate the effectiveness of proposed models and algorithms through several numerical examples. 相似文献
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Julio Flores-Gonzalez Juan Carlos Cancino-Díaz Leslie Chavez-Galan 《International journal of molecular sciences》2020,21(22)
Recent advances in the field of flow cytometry (FCM) have highlighted the importance of incorporating it as a basic analysis tool in laboratories. FCM not only allows the identification of cell subpopulations by detecting the expression of molecules in the cell membrane or cytoplasm, but it can also quantify and identify soluble molecules. The proper functioning of the FCM requires six fundamental systems, from those related to the transport of events to the systems dedicated to the analysis of information. In this review, we have identified the main considerations that every FCM user must know for an optimal antibody panel design, the quality systems that must govern the FCM protocols to guarantee reproducible results in research or clinical laboratories. Finally, we have introduced the current evidence that highlights the relevance of FCM in the investigation and clinical diagnosis of respiratory diseases, establishing important advances in the basic and clinical study of diseases as old as Tuberculosis along with the recent proposals for the monitoring and classification of patients infected with the new SARS-CoV2 virus. 相似文献
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为探究泵站压力管道的不同布置形式对管道振动的影响,选取宁夏盐环定泵站工程二泵站#1压力管道为研究对象,建立基于流固耦合的泵站压力管道水流ALGOR数值模型,并采用DASP振动测试系统获取振动信号对模拟结果进行验证,分析压力管道水流流态对管道振动的激励特征并提出优化设计方案。结果表明,压力管道进水管处、支管总管相接处及总出水管处均有强烈的振动,但进水管的振动较出水总管振动更为强烈;减振优化设计方案中,调整支管距离对降低水流对管道振动的激励效果微弱,增大管径及改变总管走向对其效果较好,其中总管走向在2°~5°之间较佳,不仅能降低管道振动,而且能减少泵站能耗损失。研究结果可为高扬程泵站压力管道的优化设计提供理论依据。 相似文献